Conveners
[LH6] Disruptive Innovations in the Biomedical Space: Science, Technology and Commercialization
- K Hun Mok (Trinity College Dublin)
Description
Throughout the history of science, it has been well proven that technological developments – be it in computational science, physics, chemistry, engineering, or mathematics – often drive further understanding and elucidation of biological/medical phenomena. The sheer quantity of Nobel Prizes in Physics or in Chemistry that are awarded to scientists who are essentially biologists (whom one would assume to receive Nobel Prizes only in the area of Physiology & Medicine) clearly attests to this.
Along with these discoveries and innovations, we are now witnessing their rapid ‘translation’ – application of these technologies to real world situations or to patients – accompanied with commercialization happening at a blindingly fast pace and on the global stage.
It is the purpose of this Scientific Session to introduce cutting-edge, disruptive technological advances and show that in many cases, such innovations have brought forth fruits of commercialization (= the founding of start-up companies). To this end, we will invite scientists and academics who are based in the physical, chemical, and/or computational sciences but who have shown that their innovations can be applied to the biomedical space. In some cases, their work have interested investors who are funding their start-up companies.
Abstracts
Around the world, the incidence of cancer is increasing every year. The surgery, radiotherapy, and chemotherapy currently being treated in hospitals are not perfect and cause a lot of pain to patients. In addition, the patient's quality of life is reduced due to side effects or sequelae after treatment. In comparison, photodynamic cancer treatment using lasers is effective for...
In lab-on-a-chip research, the technology of precisely manipulating and separating single cells holds considerable potential. This technology is crucial in revealing cell heterogeneity, mechanisms of cell functionality, and individual cells' unique characteristics, deepening our understanding of disease diagnosis and treatment. Our research has developed a Magnetophoretic circuit technology...
Magnetic Particle Imaging (MPI) is an imaging modality that uses the nonlinear magnetization characteristics of superparamagnetic iron oxide particles (SPIOs) and a relatively high magnetic moment compared to general paramagnetic materials. Since MPI can directly measure the concentration and location of SPIOs distributed in space, it is one of the emerging medical imaging techniques that are...
Synthetic DNA plays an essential role in many applications, from DNA structural nanotechnology and synthetic biology, to diagnostics and proteomics, serving as a programmable material that can enable Ångström-level positional control [1, 2]. However, to maximize the utility of DNA in these applications, additional engineering efforts are required, such as quality control or precise arrangement...
Human serum albumin (HSA) in human blood system is a significant target of oxidative stress, and severe alterations to its physiological functions can result from severe oxidative damage. The severe oxidative damage to HSA has been associated with various human diseases, including liver diseases, chronic kidney disease, cardiovascular disease, neurodegenerative disorders and cancer. As such,...
Malfunction of the skeletal muscle cells cause a wide range of problems such as developmental disorders, congenitor myopathies or dystrophies, traumatic muscle injury, and even sarcopenia. Furthermore, the importance of exercise biology is catching increasing attention in this ever-ageing demographics. While these underscore the pressing need to better understand the biology of skeletal...
