EKC2023

[P31-LH]Shikimate metabolites from Forsythia koreana flowers (Oleaceae) and their functionality as pharmacological agents

Not scheduled

20m

Poster Poster(Wed)

Speaker

Mr Jin Woo Jeang (Kyung Hee University, South Korea)

Description

Forsythia koreana (Oleaceae), a perennial shrub, is widely distributed in east Asia. From the F. koreana flowers, twenty phenolic compounds including four new ones were isolated through repeated column chromatographies and identified based on spectroscopic data such as 1D and 2D NMR, IR, FAB/MS, and CD. As well the examination of extracts, fractions, and isolated compounds was carried out for the functionality such as anti-diabetes, anti-oxidantion, and anti-inflammation. Some compounds showed significant anti-oxidant, anti-inflammatory, anti-diabetes, and whitening activity without visible toxic effect. Quantitative analysis of active materials in F. koreana flowers was also conducted using LC/MS experiments.

References

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2. Lee, Yeong-Geun, et al. "Phenylethanoid glycoside from Forsythia koreana (Oleaceae) flowers shows a neuroprotective effect." Brazilian Journal of Botany 41 (2018): 523-528.
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6. Lee, Yeong-Geun, et al. "Recovery Effect of a Rutin-Enriched Fraction Prepared From Forsythia koreana Flowers on Alloxan-Induced Pancreatic Islets in Zebrafish Larvae (Danio rerio)." Natural Product Communications 16.10 (2021): 1934578X211043731.