Conveners
[LH3] State-of-the-art technologies in biology and bioengineering: [LH4] State-of-the-art technologies in biology and bioengineering
- Juyong Yoon (the Korea Institute of Science and Technology Europe)
- Hongryeol Park (Max-Planck Institute for Molecular Biomedicine)
Description
New technologies in biology and bioengineering such as DNA sequencing, CRISPR gene editing, advanced microscopy, robotics, bioinformatics and synthetic biology are revolutionizing the field of biology with the potential to improve human health, crop yields and lead to new discoveries. These technologies are allowing scientists to read genetic code, make precise changes in the genetic code, see cells and structures in greater detail, streamline experiments, analyze and interpret large amounts of data and design and construct new biological parts, devices and systems which do not exist in the natural world.
Overall, new technologies in biology are providing scientists with the tools they need to make breakthrough discoveries and improve human health. As research continues, we can expect to see even more exciting developments in the near future.
Single-molecule fluorescence studies reveal valuable structural and functional information on biomolecules. However, conventional single-molecule methods have limited sequence diversity due to time, effort and cost constraints. To overcome this, we combine surface-based single-molecule fluorescence with next generation sequencing, enabling massively parallel single-molecule experiments for...
The migration of immune cells from one organ to another is critical for their differentiation and function1,2. T cells play critical roles in multiple sclerosis, a human disease characterized by the demyelination of neurons and detrimental damage to the nervous system3. The lung is involved in this process by accumulating myeloid cells and educating myelin-reactive T cells to be more...
The 1 subunits (CACNA1 family) of L-type voltage-gated calcium channels (LTCCs) play significant roles in brain function and neuropsychiatric disorders. Transcription of LTCCs is complex, with each 1 gene producing multiple isoforms. CACNA1S and CACNA1F were reported to have short-length transcripts from their 3’ region in the human brain which were not well characterized. Moreover, whether...
